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DEPARTMENTS
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MOLECULAR EPIDEMIOLOGY
UNIT
The Laboratory of Molecular
Epidemiology uses genetics, molecular
biology, cell biology, and molecular modeling
to examine and solve a broad range of
important biological problems. |
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Severe malaria project
The main objective
of this project is to identify that specific
and limited number of var-genes, which are
associated with virulence using DNA micro
arrays in order to facilitate production
of recombinant gene products for vaccination
or therapeutic approaches. |
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Urban
malaria control program
The main objective is to control
malaria by understanding mosquitoes behaviour
and ecology. This project involves studying
the different mosquitoes species.
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Multilateral initiative
on malaria ('mim'):
molecular epidemiology and modelling the
spread of anti-malarial drug resistance
This is the
phase II of the MIM project. It is a network
of five African countries (Tanzania, Uganda,
Ghana, Mali and Nigeria) aiming at standardising
and use common protocols to Systematically
define the characteristics of P. falciparum
resistance to selected antimalarial drugs
using multifaceted approach, the molecular
markers, in vitro drug susceptibility assays,
anti-malaria drug levels (pharmacokinetics)
and patient clinical response (in vivo efficacy).
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